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[8] SURPASS-2 : Tirzepatide (5, 10, 15 mg) reduced HbA1c by 2.01%2.30%, compared to 1.86% with semaglutide (1 mg)
Timing Follow-up Marker Blood pressure and resting heart rate Why it matters Adds cardiovascular context because retatrutide trials reported heart-rate changes in some participants
Levocarnitine promotes mitochondrial lipid oxidation in liver cells, reducing the accumulation of fat within hepatocytes
Moreover, they can be modified to express targeting ligands on their surface, enabling specific delivery to target cells or tissues and enhancing the therapeutic efficacy while reducing off-target effects of the delivered molecules [121, 220]
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